Global expression and functional analysis of human piRNAs during HSV-1 infection

Xu Wang,Pu Huang,Mengyue Lei,Ying Ma,Hongli Chen, Jing Sun,Yunzhang Hu,Jiandong Shi

Virus Research（2023）

引用 3|浏览7

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摘要

•The piRNA expression profiles of HSV-1-infected human fibroblasts identified 69 differentially expressed piRNAs.•Functional enrichment analysis revealed putative biological function of dysregulated piRNAs associated with antiviral immunity.•Two piRNAs, piRNA-hsa-28,382 and piRNA-hsa-28,190, potentially regulate HSV-1 replication.

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关键词

HSV-1,piRNA,RNA-seq,Expression pattern,Viral replication

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