Is Popularity of Fibrin Glue a Misrepresentation? A Comparative Study with Fibrin Glue and Suture Anastomosis in Rat Sciatic Nerve Injury Analysing Functional, Histological, Electrophysiological Parameters.
Neurology India（2023）
关键词
Use of fibrin has of late achieved significant popularity in nerve repairs,Whether the overzealous use of fibrin glue as a sole alternative for nerve repair justified is rather theoretical than practical,Our study points out that its use as sole agent is not justified in any circumstances as although it causes significantly less inflammation,fibrosis and neuroma formation,functionally,histologically,and electrophysiologically,its results are not promising as it shows significantly less nerve continuity,In this regard,an hybrid approach involving limited microsutures adjunct with fibrin glue can provide two benefits,firstly reduce inflammation,fibrosis,neuroma formation and secondly better nerve continuity
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