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Immune Escape of Colorectal Tumours Via Local LRH-1/Cyp11b1-mediated Synthesis of Immunosuppressive Glucocorticoids

Asma Ahmed,Cindy Reinhold,Eileen Breunig,Truong San Phan,Lea Dietrich,Feodora Kostadinova, Corinne Urwyler,Verena M. Merk,Mario Noti, Israel Toja da Silva,Konstantin Bode,Fatima Nahle,Anna Pia Plazzo,Julia Koerner,Regula Stuber,Constantin Menche,Eva Karamitopoulou,Henner F. Farin,Kenneth J. Gollob,Thomas Brunner

Molecular Oncology（2023）

Cited 7|Views33
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Key words
colorectal cancer,CYP11B1,glucocorticoids,immune checkpoint,liver receptor homolog-1 (NR5A2),tumour immune escape
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