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Gene set enrichment analysis and ingenuity pathway analysis to verify the impact of Wnt signaling in psoriasis treated with Taodan granules.

Yiran Chen,Zhan Zhang,Ying Zhang,Jingsi Jiang,Yue Luo,Xiaoya Fei,Yi Ru,Bin Li,Huiping Zhang,Taiyi Liu,Yingyao Yang,Le Kuai,Jiankun Song,Ying Luo

American journal of translational research（2023）

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Abstract
TDGs may improve psoriasis through the regulation for upstream genes (down-regulating levels of EZH2, CTNNB1, and WDR5; up-regulating TP63 levels) of Wnt signaling pathway, thus reducing levels of RAC2 and WNT5A in the Wnt signaling pathway.
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Chinese herbs,Psoriasis,Taodan granules,Wnt signaling pathway,gene set enrichment analysis,ingenuity pathway analysis
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