The efficacy of neoadjuvant EGFR -TKI therapy combined with radical surgery for stage IIIB lung adenocarcinoma harboring EGFR mutations: A retrospective analysis based on single center.

Yicheng Xiong,Dongliang Bian,Zhida Huang,Huansha Yu,Jie Huang,Peng Zhang,Wenxin He,Hongcheng Liu

Frontiers in oncology（2023）

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摘要

For stage IIIB m NSCLC patients, the prognosis might be improved by neoadjuvant -TKI followed by radical surgery versus -TKI alone, especially for those with N2 disease and harboring L858R mutation.

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关键词

adenocarcinoma,epidermal growth factor receptor,neoadjuvant targeted therapy,non-small cell lung cancer,stage IIIB

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