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Intranasal Administration of KYCCSRK Peptide Rescues Brain Insulin Signaling Activation and Reduces Alzheimer's Disease-like Neuropathology in a Mouse Model for Down Syndrome.

Antonella Tramutola,Simona Lanzillotta,Giuseppe Aceto,Sara Pagnotta,Gabriele Ruffolo,Pierangelo Cifelli,Federico Marini,Cristian Ripoli,Eleonora Palma,Claudio Grassi,Fabio Di Domenico,Marzia Perluigi,Eugenio Barone

Antioxidants (Basel, Switzerland)（2023）

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关键词
Alzheimer’s disease,DYRK1A,Down syndrome,brain insulin resistance,intellectual disability
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