PEGylated Recombinant Aplysia Punctata Ink Toxin Depletes Arginine and Lysine and Inhibits the Growth of Tumor Xenografts

Alena M. Wolkersdorfer,Birgit Bergmann,Juliane Adelmann, Matthias Ebbinghaus,Eckhard Guenther,Marcus Gutmann,Lukas Hahn,Robert Hurwitz,Ralf Kraehmer,Frank Leenders,Tessa Luehmann, Julia Schueler, Luisa Schmidt,Michael Teifel,Lorenz Meinel,Thomas Rudel

ACS BIOMATERIALS SCIENCE & ENGINEERING（2024）

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关键词
L-amino acid oxidase,PEGylation,arginine-auxotrophy,arginine lysine starvation,tumor therapy,patient-derivedtumor
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