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Design and Synthesis of Novel Rigid Dibenzo[b,f]azepines Through Ring Closure Technique As Promising Anticancer Candidates Against Leukaemia and Acting As Selective Topoisomerase II Inhibitors and DNA Intercalators.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY(2023)

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关键词
Dibenzo[bf]azepines,rigidification,ring closure,topoisomerase II,in vivo,SAR
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