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Discovery of Potent Tubulin Inhibitors Targeting the Colchicine Binding Site Via Structure-Based Lead Optimization and Antitumor Evaluation

Wei Liu,Youyou He,Zhongjie Guo,Miaomiao Wang, Xiaodong Han,Hairui Jia,Jin He,Shanshan Miao,Shengzheng Wang

Journal of Enzyme Inhibition and Medicinal Chemistry（2023）

Cited 4|Views2
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Key words
Tubulin inhibitors,colchicine binding site,structural optimisation,antitumour activity
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