Neuromuscular and cardiac adverse events associated with immune checkpoint inhibitors: pooled analysis of individual cases from multiple institutions and literature

•Myocarditis and myositis represent rare but potentially lethal irAEs.•There is no standard management of these irAEs due to the lack of consistent data.•This is the largest pooled analysis of individual cases of myocarditis/myositis related to ICIs.•Early onset and the concurrent manifestation of myositis and myocarditis are associated with worse outcomes.