Editorial: Machine learning, epistasis, and protein engineering: From sequence-structure-function relationships to regulation of metabolic pathways.

Laboratory of Excellence LABEX GR, DSIMB, Inserm UMR S1134, University of Paris City and University of Reunion, Paris, France, PEACCEL, Artificial Intelligence Department, Paris, France, Department of Biochemistry, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico, Science for Life Laboratory, School of Engineering Sciences in Chemistry, Biotechnology, and Health, KTH Royal Institute of Technology, Stockholm, Sweden, Department of Fibre and Polymer Technology, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm, Sweden, Aix Marseille University, CNRS, UMR7281 Bioénergétique et Ingénierie des Protéines, Marseille, France