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Analysis of Retinal Nerve Layers in Idiopathic, LRRK2-associated Parkinson's Disease and Unaffected Carriers of G2019S Mutation.

PARKINSONISM & RELATED DISORDERS(2023)

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摘要
•The peripapillary retinal nerve fiber layer of the retina is thinned in idiopathic PD.•In LRRK2-PD there seems to be minor or absent retinal thinning.•OCT might not to be useful to differentiate clinical or asymptomatic LRRK2-PD from healthy controls.
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关键词
LRRK2,Optical coherence tomography,Parkinson's disease,Retina,Biomarker,123I-ioflupane
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