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EIF4A Inhibition Targets Bioenergetic Homeostasis in AML MOLM-14 Cells in Vitro and in Vivo and Synergizes with Cytarabine and Venetoclax.

Katie Fooks,Gabriela Galicia-Vazquez,Victor Gife,Alejandro Schcolnik-Cabrera,Zaynab Nouhi,William W. L. Poon,Vincent Luo,Ryan N. Rys,Raquel Aloyz,Alexandre Orthwein,Nathalie A. Johnson,Laura Hulea,Francois E. Mercier

Journal of experimental & clinical cancer research（2022）

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关键词
AML,eIF4A,BCL2,MCL1,BCL-XL,mTORC1,Metabolism,ROS,Bioenergetics,araC,Venetoclax
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