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Superiority of intranasal over systemic administration of bioengineered soluble ACE2 for survival and brain protection against SARS-CoV-2 infection

Luise Hassler,Jan Wysocki,Jared T. Ahrendsen,Minghao Ye,Ian Gelarden,Vlad Nicolaescu,Anastasia Tomatsidou,Haley Gula,Cosimo Cianfarini,Nigar Khurram,Yashpal Kanwar,Benjamin D. Singer,Glenn Randall,Dominique Missiakas,Jack Henkin,Daniel Batlle

bioRxiv (Cold Spring Harbor Laboratory)（2022）

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Key words
soluble ace2,brain protection,intranasal,sars-cov
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