FXR Inhibition May Protect from SARS-CoV-2 Infection by Reducing ACE2

Teresa Brevini,Mailis Maes,Gwilym J. Webb,Binu V. John,Claudia D. Fuchs,Gustav Buescher,Lu Wang,Chelsea Griffiths,Marnie L. Brown,William E. Scott III,Pehuén Pereyra-Gerber,William T. H. Gelson,Stephanie Brown,Scott Dillon,Daniele Muraro,Jo Sharp,Megan Neary,Helen Box,Lee Tatham,James Stewart,Paul Curley,Henry Pertinez,Sally Forrest,Petra Mlcochova,Sagar S. Varankar,Mahnaz Darvish-Damavandi,Victoria L. Mulcahy,Rhoda E. Kuc,Thomas L. Williams,James A. Heslop,Davide Rossetti,Olivia C. Tysoe,Vasileios Galanakis,Marta Vila-Gonzalez,Thomas W. M. Crozier,Johannes Bargehr,Sanjay Sinha,Sara S. Upponi,Corrina Fear,Lisa Swift,Kourosh Saeb-Parsy,Susan E. Davies,Axel Wester,Hannes Hagström,Espen Melum, Darran Clements,Peter Humphreys,Jo Herriott,Edyta Kijak,Helen Cox,Chloe Bramwell,Anthony Valentijn,Christopher J. R. Illingworth,Bassam Dahman,Dustin R. Bastaich,Raphaella D. Ferreira,Thomas Marjot,Eleanor Barnes,Andrew M. Moon,Alfred S. Barritt IV,Ravindra K. Gupta,Stephen Baker,Anthony P. Davenport,Gareth Corbett,Vassilis G. Gorgoulis,Simon J. A. Buczacki,Joo-Hyeon Lee,Nicholas J. Matheson,Michael Trauner,Andrew J. Fisher,Paul Gibbs,Andrew J. Butler,Christopher J. E. Watson,George F. Mells,Gordon Dougan,Andrew Owen,Ansgar W. Lohse,Ludovic Vallier,Fotios Sampaziotis

Nature（2022）

引用 128|浏览64

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关键词

Adjuvants,Preclinical research,SARS-CoV-2,Translational research,Viral infection,Science,Humanities and Social Sciences,multidisciplinary

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