Discovery of GDC-0077 (Inavolisib), a Highly Selective Inhibitor and Degrader of Mutant PI3K
Emily J. Hanan,Marie-Gabrielle Braun,Robert A. Heald,Calum MacLeod,Connie Chan,Saundra Clausen,Kyle A. Edgar,Charles Eigenbrot,Richard Elliott,Nicholas Endres,Lori S. Friedman,Emily Gogol,Xiao-Hui Gu, Rebecca Hong Thibodeau,Philip S. Jackson,James R. Kiefer,Jamie D. Knight,Michelle Nannini,Raman Narukulla,Amanda Pace,Jodie Pang,Hans E. Purkey,Laurent Salphati,Deepak Sampath,Stephen Schmidt,Steve Sideris,Kyung Song,Swathi Sujatha-Bhaskar,Mark Ultsch,Heidi Wallweber,Jianfeng Xin, SiewKuen Yeap,Amy Young,Yu Zhong,Steven T. Staben JOURNAL OF MEDICINAL CHEMISTRY(2022)
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