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Occupational Exposure to Carcinogens in the European Union

Occupational and environmental medicine(2000)SCI 2区

FIOH

Cited 516|Views12
Abstract
Objectives-To construct a computer assisted information system for the estimation of the numbers of workers exposed to established and suspected human carcinogens In the member states of the European Union (EU).Methods-A database called CAREX (carcinogen exposure) was designed to provide selected exposure data and documented estimates of the number of workers exposed to carcinogens by country, carcinogen, and industry. CAREX includes data on agents evaluated by the International Agency for Research on Cancer (IARC) (all agents in groups 1 and 2A as of February 1995, and selected agents in group 2B) and on ionising radiation, displayed across the 55 industrial classes. The 1990-3 occupational exposure was estimated in two phases. Firstly, estimates were generated by the CAREX system on the basis of national labour force data and exposure prevalence estimates from two reference countries (Finland and the United States) which had the most comprehensive data available on exposures to these agents. For selected countries, these estimates were then refined by national experts in view of the perceived exposure patterns in their own countries compared with those of the reference countries.Results-About 32 million workers (23% of those employed) in the EU were exposed to agents covered by CAREX. At least 22 million workers were exposed to IARC group 1 carcinogens. The exposed workers had altogether 42 million exposures (1.3 mean exposures for each exposed worker). The most common exposures were solar radiation (9.1 million workers exposed at least 75% of working time), environmental tobacco smoke (7.5 million workers exposed at least 75% of working time), crystalline silica (3.2 million exposed), diesel exhaust (3.0 million), radon (2.7 million), and wood dust (2.6 million).Conclusion-These preliminary estimates indicate that in the early 1990s, a substantial proportion of workers in the EU were exposed to carcinogens.
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exposure,carcinogen,Europe
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要点】:本文构建了一个计算机辅助信息系统CAREX,用于估计欧盟成员国工人暴露于已知和疑似人类致癌物的数量,发现约32百万工人(占就业人数的23%)暴露于CAREX所涵盖的致癌物。

方法】:设计CAREX数据库,提供特定国家、特定致癌物和行业的工人暴露数据,使用芬兰和美国的暴露数据作为参考,结合各国劳动力数据和暴露率估计。

实验】:通过CAREX系统对1990-1993年间职业暴露进行估计,并根据各国专家对暴露模式的评估进行数据修正,使用的数据集未明确提及,但涉及国际癌症研究机构(IARC)分组1和2A的致癌物以及部分2B组致癌物。结果显示,约32百万工人暴露于致癌物,其中至少22百万工人暴露于IARC组1致癌物。