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T-cell Replete Cord Transplants Give Superior Outcomes in High-Risk and Relapsed/refractory Pediatric Myeloid Malignancy

Claire Horgan,Khushnuma Mullanfiroze,Archana Rauthan,Katharine Patrick,Naeem Akram Butt,Oana Mirci-Danicar,Olya O'Connor,Caroline Furness,Akshay Deshpande,Sarah Lawson,Valerie Broderick,Pamela Evans,Brenda Gibson,Wing Roberts,Salah Ali,Sevasti Galani,Amy A. Kirkwood,Jelena Jovanovic,Richard Dillon,Paul Virgo,Beki James,Kanchan Rao,Persis J. Amrolia,Robert F. Wynn

Blood advances（2023）

Cited 7|Views26
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Abstract
Key Points • Compared with other cell sources, TRCB transplant results in improved disease-free survival and relapse risk in pediatric AML/MDS.• Compared with other cell sources, cord-transplant cures with less chronic GvHD and particularly improves GvHD-free, relapse-free survival.
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Treatment Outcomes
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