Biological and prognostic implications of biopsy upgrading for high-grade upper tract urothelial carcinoma at nephroureterectomy.

International journal of urology : official journal of the Japanese Urological Association(2023)

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摘要
High tumor grade on URS biopsy is associated with features of biologically and clinically aggressive UTUC tumors. URS low-grade UTUC that becomes upgraded to high-grade might carry a better prognosis than high-grade UTUC on URS. Tumor specific factors are likely to be responsible for upgrading to high-grade on RNU.
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关键词
biopsy grade,intratumor heterogeneity,survival,upgrading,upper tract urothelial carcinoma
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