Design, synthesis and chemoinformatic studies of new thiazolopyrimidine derivatives as potent anticancer agents via phosphodiesterase-5 inhibition and apoptotic inducing activity
Journal of Molecular Structure（2023）
关键词
Thiazolo[3,2-a]pyrimidine derivatives,Biginelli reaction,Phosphodiesterase-5 inhibitors,cytotoxic activity,Apoptosis,Lipophilicity metrics,ADMET
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