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Treatment of HCC with Claudin-1-specific Antibodies Suppresses Carcinogenic Signaling and Reprograms the Tumor Microenvironment.

Natascha Roehlen,Marion Muller,Zeina Nehme,Emilie Crouchet,Frank Juhling,Fabio Del Zompo,Sara Cherradi,Francois H. T. Duong,Nuno Almeida,Antonio Saviano,Mirian Fernandez-Vaquero,Tobias Riedl,Houssein El Saghire,Sarah C. Durand,Clara Ponsolles,Marine A. Oudot,Romain Martin,Nicolas Brignon,Emanuele Felli,Patrick Pessaux, Antonin Lallement,Irwin Davidson,Simonetta Bandiera,Christine Thumann,Patrice Marchand,Solange Moll,Brandon Nicolay,Nabeel Bardeesy,Yujin Hoshida,Mathias Heikenwaelder,Roberto Iacone,Alberto Toso,Markus Meyer,Greg Elson,Tamas Schweighoffer,Geoffrey Teixeira,Mirjam B. Zeisel,Patrice Laquerriere,Joachim Lupberger,Catherine Schuster,Laurent Mailly,Thomas F. Baumert

Journal of hepatology（2023）

Cited 5|Views75
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Key words
Liver cancer,tight junction,CLDN1,HCC,plasticity,resistance,stemness,tumor immune microenvironment
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