Forever young: Sphk2 in HSCs, when less is more.

Blood(2022)

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摘要
In this issue of Blood, Li et al1 use different mouse models to comprehensively dissect the role of sphingosine kinases (Sphks) in the regulation of hematopoietic stem cell (HSC) function, uncovering that specific loss of Sphk2 expands and functionally rejuvenates HSCs.
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hscs,young
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