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Large-Area SiPM Pixels (lasips) in SPECT

Journal of instrumentation(2022)

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摘要
A standard camera for Single Photon Emission Computed Tomography (SPECT) contains 50-100 photomultiplier tubes (PMTs) that occupy at least 50% of its volume. It is shielded by a thick layer of lead which makes it heavy and bulky. Replacing PMTs by silicon photomultipliers (SiPMs) could significantly reduce the weight and size of a SPECT camera. However, the main obstacle is the limited size of SiPMs: even with the largest commercially available SiPM of 6 x 6 mm(2) a few thousand channels would be needed to fill a camera. As a solution, we propose to use Large Area SiPM Pixels (LASiPs) which are built by summing the currents of several SiPMs into a single output. We developed a LASiP prototype summing 8 SiPMs using the MUSIC ASIC. To test the feasibility of using this solution in SPECT, we built a proof-of-concept micro camera that consisted of four of our LASiP prototypes coupled to a 40 x 40 x 8 mm(3) NaI(Tl) crystal. We were able to reconstruct simple images of a Tc-99m capillary with an intrinsic spatial resolution of similar to 2mm and an energy resolution of similar to 11.6%. We also simulated the system with Geant4, finding a good agreement with our experimental results. The simulations were extended to a larger camera, aiming to study the impact of pixel size, shape and noise.
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关键词
Gamma camera, SPECT, PET PET/CT, coronary CT angiography (CTA),Medical-mage reconstruction methods and algorithms, computer-aided diagnosis,Medical-image reconstruction methods and algorithms, computer-aided software
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