Sustained delivery of the bone morphogenetic proteins BMP-2 and BMP-7 for cartilage repair and regeneration in osteoarthritis
Osteoarthritis and Cartilage Open(2022)
Abstract
This study showed that the sustained release of GF from PODS BMPs is effective in promoting chondrogenesis . The small animal data suggests that this novel approach of delivering therapeutic proteins sustainably and locally to the knee has promise for developing future disease-modifying therapies of OA.
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Key words
PODS,BMP-7,BMP-2,Sustained release,Joint osteoarthritis,Cartilage regeneration
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