Maternal Periconceptional Folic Acid Supplementation and DNA Methylation Patterns in Adolescent Offspring.

Krista S Crider,Arick Wang,Hao Ling,Nancy Potischman,Regan L Bailey,Yang Lichen,Christine M Pfeiffer,J Keith Killian,Charles Rose,Joshua Sampson,Li Zhu,Robert J Berry,Martha Linet,Wang Yu,L Joseph Su

The Journal of nutrition（2023）

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摘要

Overall, there were no differences in DNA methylation between adolescents who were exposed during the critical developmental window and those not exposed to the recommended periconceptional/first-trimester dosage of folic acid.

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关键词

DNA methylation,adolescents,dietary supplements,epigenetic,folic acid,periconceptional,pregnancy

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