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A Molecularly Engineered, Broad-Spectrum Anti-Coronavirus Lectin Inhibits SARS-CoV-2 and MERS-CoV Infection in Vivo

Jasper Fuk-Woo Chan,Yoo Jin Oh,Shuofeng Yuan,Hin Chu,Man-Lung Yeung,Daniel Canena,Chris Chung-Sing Chan,Vincent Kwok-Man Poon,Chris Chun-Yiu Chan,Anna Jinxia Zhang,Jian-Piao Cai,Zi-Wei Ye,Lei Wen,Terrence Tsz-Tai Yuen,Kenn Ka-Heng Chik,Huiping Shuai,Yixin Wang,Yuxin Hou,Cuiting Luo,Wan-Mui Chan,Zhenzhi Qin,Ko-Yung Sit,Wing-Kuk Au,Maureen Legendre,Rong Zhu,Lisa Hain,Hannah Seferovic,Robert Tampe,Kelvin Kai-Wang To,Kwok-Hung Chan,Dafydd Gareth Thomas,Miriam Klausberger,Cheng Xu,James J. Moon,Johannes Stadlmann,Josef M. Penninger,Chris Oostenbrink,Peter Hinterdorfer,Kwok-Yung Yuen,David M. Markovitz

Cell Reports Medicine（2022）

Cited 27|Views43
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Key words
antiviral,atomic force microscopy,banana,coronavirus,lectin,MERS-CoV,SARS-CoV-2,single-molecule force spectroscopy,spike,treatment
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