Synthesis of Novel Nanostructured Copper Tungstate/gce Electrochemical System in Deep Eutectic Solvent Medium for Simultaneous Detection of Dopamine and Paracetamol

Deep Eutectic Solvent (DES) based systems are considered as eco-friendly approach, it can be applied to prepare copper tungstate nanorods with nanometer-size ranges. The synthesis of a novel nanostructured CuWO4/GCE electrochemical system in Deep Eutectic Solvent medium is described in the present study. Detailed character-ization studies have been carried out to observe the surface morphology, crystallinity, and elemental composition of the nanocrystalline CuWO4. Cyclic voltammetry (CV) and electrochemical impedance studies (EIS) provide electrochemical and interfacial electron transfer characteristics of the CuWO4/GCE system in 0.1 M phosphate buffer medium. The synthesized CuWO4/GCE electrode is exploited for both individual and simultaneous elec-trochemical detection of biologically important molecules dopamine (DA) and paracetamol (PAR) in the phys-iological pH range. The proposed system exhibits an enhanced current response towards electrochemical oxidation of DA and PAR and it can be extended to use further for the electrochemical determination in bio-logical as well as pharmaceutical formulations in nanomolar concentration ranges. Differential pulse voltam-metry method was applied to determine a wider linear concentration in the range of 6.0 x 10-7-26 x 10-5 M and 6.0 x 10-7-30 x 10-5 M, under the optimized experimental conditions, for DA and PAR, respectively. Because of enhanment in electrocatalytic properties, excellent sensitivity, and long-term stability, the prepared CuWO4/GCE sensor can be considered a novel promising system for sensing dopamine and paracetamol.