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KIR-based Inhibitory CARs Overcome CAR-NK Cell Trogocytosis-Mediated Fratricide and Tumor Escape

Ye Li,Rafet Basar,Guohui Wang,Enli Liu,Judy S. Moyes, Li,Lucila N. Kerbauy,Nadima Uprety,Mohsen Fathi,Ali Rezvan,Pinaki P. Banerjee,Luis Muniz-Feliciano,Tamara J. Laskowski,Emily Ensley,May Daher,Mayra Shanley,Mayela Mendt,Sunil Acharya,Bin Liu,Alexander Biederstädt,Hind Rafei,Xingliang Guo,Luciana Melo Garcia,Paul Lin,Sonny Ang,David Marin,Ken Chen,Laura Bover,Richard E. Champlin,Navin Varadarajan,Elizabeth J. Shpall,Katayoun Rezvani

Nature Medicine（2024）

Cited 38|Views64
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Key words
NK Cell Activation,CAR T Cells,NK Cell Therapy,NK Cell Recognition,NK Cell Development
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