Molecular design, synthesis and biological evaluation of novel 1,2,5-trisubstituted benzimidazole derivatives as cytotoxic agents endowed with ABCB1 inhibitory action to overcome multidrug resistance in cancer cells
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY（2022）
关键词
Multidrug resistnce (MDR), ABCB1 transporter, benzimidazole, ligand based pharmacophore, molecular modelling
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