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Phosphodiesterase inhibitor for heart failure with preserved ejection fraction: A systematic review and meta-analysis

Zhu Chen,Kaixuan Zhao,Changhu Xiao,Ziyu He,Sha Liu,Xuemei Wu,Shuting Shi,Yuan Guo

Saudi Pharmaceutical Journal（2022）

Cited 1|Views15
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Abstract
PDE inhibitors did not effectively improve LV function, PAP, exercise capacity, and QOL in patients with HFpEF. However, they improved RV function with significant difference, suggesting that PDE inhibitors might be a promising option for HFpEF patients with RV dysfunction.
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Key words
Phosphodiesterase inhibitor,Heart failure with preserved ejection fraction,Right ventricular dysfunction,Meta-analysis
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