Structure and Function of Mycobacterial Arabinofuranosyltransferases.
Sub-cellular biochemistry(2022)
摘要
The mycobacteria genus is responsible for numerous infectious diseases that have afflicted the human race since antiquity-tuberculosis and leprosy in particular. An important contributor to their evolutionary success is their unique cell envelope, which constitutes a quasi-impermeable barrier, protecting the microorganism from external threats, antibiotics included. The arabinofuranosyltransferases are a family of enzymes, unique to the Actinobacteria family that mycobacteria genus belongs to, that are critical to building of this cell envelope. In this chapter, we will analyze available structures of members of the mycobacterial arabinofuranosyltransferase, clarify their function, as well as explore the common themes present amongst this family of enzymes, as revealed by recent research.
更多查看译文
关键词
Acyl carrier protein,Arabinofuranosyltransferases,Arabinogalactan,Arabinosyltransferases,Cell wall biosynthesis,Cryo-EM,Cryogenic electron microscopy,Glycosyltransferases,Lipoarabinomannan,Mycobacterium,Sugar transfer,Tuberculosis,X-ray crystallography
AI 理解论文
溯源树
样例
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要