Nerve agents surrogates: synthetic approaches and uses thereof for analytical and toxicological purposes

In the field of Chemical Defense toward Nerve Agents, the development of analytical methodologies for analysis of different sample matrices, training of human resources in handling, detection of such toxic chemicals, and design of more effective medical countermeasures may be hampered by the lack of infrastructure and well-prepared human resources. Therefore Nerve Agents Surrogates may be an invaluable alternative to accomplish such tasks, as these compounds present similar behavior and are easier to handle in comparison to actual nerve agents, being useful analytical and toxicological tools for technical purposes.