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Persistent circulating SARS-CoV-2 spike is associated with post-acute COVID-19 sequelae.

Zoe Swank,Yasmeen Senussi,Zachary Manickas-Hill, Xu G Yu,Jonathan Z Li,Galit Alter,David R Walt

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America（2022）

Cited 104|Views5
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Abstract
The diagnosis of post-acute sequelae of COVID-19 (PASC) poses an ongoing medical challenge. To identify biomarkers associated with PASC we analyzed plasma samples collected from PASC and COVID-19 patients to quantify viral antigens and inflammatory markers. We detect SARS-CoV-2 spike predominantly in PASC patients up to 12 months post-diagnosis.
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COVID-19,SARS-CoV-2 antigens,long COVID,post-acute sequelae of COVID-19 (PASC),spike
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