Impact of SARS-CoV-2 Omicron variants on serum neutralization in a cohort of healthcare workers vaccinated with BNT162b2

Anna Gidari,Elisabetta Schiaroli,Samuele Sabbatini,Sabrina Bastianelli,Sara Pierucci,Chiara Busti,Daniela Francisci

The Journal of infection（2022）

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摘要

•Omicron variants are less efficiently neutralized by BNT162b2 elicited serum.•Vaccine-elicited serums maintain the neutralizing potency for B.1.617.2.•NT-Abs titer progressively decreases over time.•Vaccine-elicited sera have lower efficiency against BA.5 than the other omicron VOCs.

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关键词

COVID-19,SARS-CoV-2,antibodies,neutralizing,omicron,vaccine,variant

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