Combined Hepatocellular-Cholangiocarcinoma Derives from Liver Progenitor Cells and Depends on Senescence and IL-6 Trans-Signaling
Nofar Rosenberg,Matthias Van Haele,Tali Lanton,Neta Brashi,Zohar Bromberg,Hanan Adler,Hilla Giladi,Amnon Peled,Daniel S. Goldenberg,Jonathan H. Axelrod,Alina Simerzin,Chofit Chai,Mor Paldor,Auerlia Markezana,Dayana Yaish,Zohar Shemulian,Dvora Gross,Shanny Barnoy,Maytal Gefen, Osher Amran,Sofie Claerhout,Mirian Fernandez-Vaquero,Maria Garcia-Beccaria,Danijela Heide,Michal Shoshkes-Carmel, Dirk Schmidt Arras,Sharona Elgavish,Yuval Nevo,Hadar Benyamini,Janina E. E. Tirnitz-Parker,Aranzazu Sanchez,Blanca Herrera,Rifaat Safadi, Klaus H. Kaestner,Stefan Rose-John,Tania Roskams,Mathias Heikenwalder,Eithan Galun Journal of Hepatology（2022）
Key words
Cancer stem cells,Hepatocarcinogenesis,Oval cells,Inflammation-induced cancer
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