Metformin Mitigates Stress-Induced Premature Senescence by Upregulating AMPKα at Ser485 Phosphorylation Induced SIRT3 Expression and Inactivating Mitochondrial Oxidants.
Mechanisms of ageing and development（2022）
Key words
Metformin,VSMC senescence,Mitochondrial ROS,P-AMPK (Ser485),SIRT3,SOD2 acetylation
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