Development and Validation of a Neonatal Physical Maturity Score for Low- and Middle-Income Countries
AMERICAN JOURNAL OF PERINATOLOGY(2024)
摘要
Objective Currently available gestational age scoring systems are complex and inaccurate for wider use in low- and middle-income countries (LMIC), particularly in infants with neonatal encephalopathy. Here, we aimed to develop a scoring system based on physical characteristics for identifying late preterm infants from term infants. Study Design This was a prospective observational study conducted in 2 phases- the discovery phase and validation phase. In the first phase, we examined the accuracy of 10 objective physical characteristics in a prospective cohort of 1,006 infants recruited from three hospitals in South India. A weighted scoring system and a photo card were then developed based on the six best performing characteristics which were validated in another prospective cohort of 1,004 infants. Results The final score had a sensitivity of 66.0% (95% confidence intervals [CIs], 58.4-73.8%), specificity of 80.0% (95% CI, 77.2-82.7%), and a negative predictive value of 93.0% (95% CI, 90.5-94.5%). Conclusion This scoring system may have wider applications in LMIC, particularly in community settings and in infants with neonatal encephalopathy.
更多查看译文
关键词
newborn,gestational assessment,preterm infants,low- and middle-income countries
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要