Primary basal cell carcinoma of the prostate with concurrent acinar adenocarcinoma and ductal adenocarcinoma: A case report and literature review

Introduction: Prostatic basal cell carcinoma (PBCC) with concurrent acinar adenocarcinoma and ductal adenocarcinoma is an extremely rare tumor that can exhibit various morphological features, as well as clinical spectrums of the disease. Case presentation: A 59-year-old male presented to the Department of Urology with two years of lower urinary tract symptoms. The ultrasound examination in Minqin County people's Hospital exhibited benign prostatic hyperplasia with calcification. After administration of ineffective medication, the patient underwent transurethral resection of the prostate (TURP). Pathological examination revealed a diagnosis of PBCC. Subsequently, robot-assisted radical prostatectomy was performed, which confirmed a diagnosis of prostatic basal cell carcinoma with coexisting acinar adenocarcinoma and ductal adenocarcinoma. Conclusion: Although most cases of prostatic basal cell carcinoma are indolent, rather than aggressive, there are no reliable methods that are able to distinguish these presentations. Furthermore, an optimal treatment has not yet been established. Radical surgery is recommended if PBCC is diagnosed at an early stage.