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A Gene Dosage‐dependent Effect Unveils NBS1 As Both a Haploinsufficient Tumour Suppressor and an Essential Gene for SHH‐medulloblastoma

Marialaura Petroni,Francesca Fabretti,Stefano Di Giulio,Vittoria Nicolis di Robilant, Veronica La Monica,Marta Moretti,Francesca Belardinilli,Francesca Bufalieri,Anna Coppa,Paola Paci,Alessandro Corsi,Enrico De Smaele,Sonia Coni,Gianluca Canettieri,Lucia Di Marcotullio,Zhao-Qi Wang,Giuseppe Giannini

Neuropathology & applied neurobiology/Neuropathology and applied neurobiology（2022）

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关键词
haploinsufficiency,MRN complex,Nijmegen breakage syndrome,Notch,Sonic Hedgehog
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