Size-dependent cellular uptake and sustained drug release of PLGA particles
Particuology（2023）
Abstract
•Drug loading of micrometer DEX-loaded PLGA particles (DPs) was higher than that of submicrometer DPs.•At submicrometer scale, 500 nm DPs showed a better sustained release profile.•500 nm DPs had sustained anti-inflammatory efficacy in lipopolysaccharide-induced RAW 264.7 cells model.
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Key words
DEX-loaded PLGA particles (DPs),Sustained release,Anti-inflammatory efficacy
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