SO-29 Dihydropyrimidine Dehydrogenase (DPD) Genotype and Phenotype among Danish Cancer Patients: Prevalence and Correlation Between DPYD-genotype Mutations and P-uracil Concentrations

Niels Herluf Paulsen , Camilla Qvortrup, Fie Juhl Vojdeman, Peter Plomgaard, Stig Ejdrup Andersen , Anne Ramlov, Birgitte Bertelsen, Maria Rossing, Claus Gyrup Nielsen, Elke Hoffmann-L€ ucke , Eva Greibe, Hanne Spangsberg Holm, Heidi Hvid Nielsen, Ihab Bishara Yousef Lolas, Jonna Skov Madsen , Marianne Lerbaek Bergmann, Morten Mørk, Palle B. Nielsen Fruekilde, Pernille Bøttger, Peter Clausager Petersen, Peter Henrik Nissen , Søren Feddersen , Troels K. Bergmann, Per Pfeiffer and Per Damkier Department of Clinical Pharmacology, Odense University Hospital, Odense, Denmark; Clinical Pharmacology, Pharmacy and Environmental Medicine Department of Public Health, University of Southern Denmark, Odense, Denmark; Department of Oncology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Department of Clinical Biochemistry, Holbaek Hospital, Holbaek, Denmark; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark; Clinical Pharmacology Unit, Zealand University Hospital, Roskilde, Denmark; Department of Oncology, Aarhus University Hospital, Aarhus, Denmark; Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark; Center for Genomic Medicine, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark; Department of Clinical Biochemistry, Aarhus University Hospital, Aarhus N, Denmark; Institute for Clinical Medicine, Aarhus University of Health, Aarhus, Denmark; Department of Oncology, Odense University Hospital, Odense, Denmark; Department of Clinical Biochemistry, Zealand University Hospital, Køge, Denmark; Department of Molecular Diagnostics, Aalborg University Hospital, Aalborg, Denmark; Department of Biochemistry and Immunology, Lillebaelt Hospital – University Hospital of Southern Denmark, Vejle, Denmark; Department of Regional Health Research, University of Southern Denmark, Odense, Denmark; Department of Clinical Biochemistry, Odense University Hospital, Odense, Denmark; Department of Oncology, Zealand University Hospital, Roskilde, Denmark; Denmark and Institute for Clinical Medicine, Aarhus University, Aarhus, Denmark; Department of Clinical Research, University of Southern Denmark, Odense, Denmark; Department of Regional Health Research, University of Southern Denmark, Esbjerg, Denmark