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Single Nucleotide Polymorphism in Interleukin-6 and Interleukin-8 Genes of Equines

Sanjeev Kumar, Mohammad Ashraf,Urmila Pannu,Sharat Chandra Mehta

Journal of Equine Veterinary Science(2022)

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摘要
•Genetic variations in the myokine genes (IL-6 and IL-8) of equines.•An intronic SNP (C>T) at position Equcab3.0:4:54607583 in IL-6 gene of Poitou donkey.•An intronic SNP at position EquCab3.0:3:63720770 and exonic SNP (G > C) at position EquCab3.0:3:63720817 leading to a change in amino acid from leucine to phenylalanine in IL-8 gene of studied equines.•SNP (G>C) in 5’ UTR of IL-8 gene in Poitou donkey at position EquCab3.0:3: 63720883.
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关键词
Myokine,Cytokine,IL-6,CXCL8,SNPs
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