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Dominant-acting CSF1R variants cause microglial depletion and altered astrocytic phenotype in zebrafish and adult-onset leukodystrophy

Berdowski Woutje M.,van der Linde Herma C.,Breur Marjolein,Oosterhof Nynke,Beerepoot Shanice,Sanderson Leslie, Wijnands Lieve I., de Jong Patrick,Tsai-Meu-Chong Elisa,de Valk Walter,de Witte Moniek,van IJcken Wilfred F. J.,Demmers Jeroen,van der Knaap Marjo S.,Bugiani Marianna,Wolf Nicole I.,van Ham Tjakko J.

Acta Neuropathologica（2022）

引用 8|浏览45
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关键词
Microglia,CSF1R,Leukodystrophy,ALSP,Zebrafish models,Astrocytes
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