Metal–Organic Framework-Based Nanostructures for Biomedical Applications

The progressive structural activities of nanomaterials are required for tracking potential applications in the field of biomedical sciences for an instance, sustained and targeted drug delivery, bio-catalysis, bio-separation, biosensing, magnetic resonance imaging, bioremediation of toxic metals, and many more. In this context, the metal–organic framework-based nanostructures (MOFsN) have been considered as an ideal material to be applied in the significant areas of research to develop next-generation technology particularly in the biomedical sciences. The MOFsN frameworks are organic–inorganic crystalline metal complexes with a systematic arrangement of charged metal ions, bounded through highly functional organic molecules together which will produce innumerable binding sites and cage-like structure. Thus, the synthesis of such architectural and potential molecules is beneficial as a new thrust area for multipurpose, multitasking, multitracking, and multifaceted nanomaterials with greater reactivity and biocompatibility to catalyze biochemical and biomedical processes.In the development of nanotechnology, MOFsN with highly surface engineered nanomaterials has emerged in order to enhance the structural potential and activities as compared to nanoscale particles. This chapter deals with the up-to-date progress of MOFsN being cost effective, highly active, and higher surface energy nanomaterials for using them in various fields related to their biological applications challenges and perspectives such as drug delivery, bio-imaging, biosensing, and biocatalysis.