Resolution of Epileptic Spasms after Drainage of Chronic Subdural Hematoma Related to Nonaccidental Traumatic Brain Injury

Epileptic spasms (ES), an age-related seizure type, can occur due to a traumatic brain injury (TBI), after a seizure-free latency period.Its pathophysiological process is not fully understood.We report the case of a 5-month-old infant that presented an extensive encephalomalacia, right greater than left, and bilateral subdural hematomas secondary to nonaccidental TBI.Two months post-injury, the patient developed drug-resistant asymmetric ES, primarily involving the left limbs.The diagnosis was established based on electroclinical features.Subsequent brain magnetic resonance imaging (MRI) disclosed a progression of the left chronic subdural collection with associated mass effect.The subdural collection was drained, and resolution of ES was gradually observed after the procedure.This clinical report highlights the resolution of ES associated to nonaccidental TBI after drainage of a chronic subdural hematoma.The chronological association between these two events may provide some insight into the pathological mechanism underlying ES.