Smart Contact Lens with Dual‐Sensing Platform for Monitoring Intraocular Pressure and Matrix Metalloproteinase‐9 (Adv. Sci. 12/2022)

Dual-functional Smart Contact Lens In article number 2104738, Jia Qu, Xiaohu Liu, Yi Wang, and co-workers present a contact lens sensor that enables the simultaneous detection of two markers associated with ocular disease: intraocular pressure (IOP) and matrix metalloproteinase-9 (MMP-9). An anti-opal structure in contact lens provides continuously monitoring of IOP by its color changes, while a gold nanobowl substrate offers the Raman detection of MMP-9.