miR-203 represses keratinocyte stemness by targeting survivin.

Florian Labarrade,Jean-Marie Botto, Isabelle Marie Imbert

Journal of cosmetic dermatology（2022）

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摘要

In summary, our findings suggest that miR-203 target 3'UTR region of survivin mRNA and directly represses survivin expression in the epidermis. The rice extract was identified as modulator of miR-203 and pointed out as a promising microRNA-based strategy in treating skin changes occurring with aging.

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关键词

differentiation,genetic analysis,miR-203,skin barrier,skin physiology/structure

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