Early Combination Therapy with Immunoglobulin and Steroids is Associated with Shorter ICU Length of Stay in Multisystem Inflammatory Syndrome in Children (MIS‐C) Associated with COVID‐19: A Retrospective Cohort Analysis from 28 U.S. Hospitals

Suggested therapeutic options for Multisystem Inflammatory Syndrome in Children (MIS‐C) include intravenous immunoglobulins (IVIG) and steroids. Prior studies have shown the benefit of combination therapy with both agents on fever control or the resolution of organ dysfunction. The primary objective of this study was to analyze the impact of IVIG and steroids on hospital and ICU length of stay (LOS) in patients with MIS‐C associated with Coronavirus Disease 2019 (COVID‐19).