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Defining the Spatial Distribution of Extracellular Adenosine Revealed a Myeloid-Dependent Immunosuppressive Microenvironment in Pancreatic Ductal Adenocarcinoma

Vincenzo Graziano,Andreas Dannhorn,Heather Hulme,Kate Williamson,Hannah Buckley,Saadia A. Karim, Matthew Wilson,Sheng Y. Lee,Brajesh P. Kaistha,Sabita Islam,James E. D. Thaventhiran,Frances M. Richards,Richard Goodwin,Rebecca Brais,Jennifer P. Morton,Simon J. Dovedi,Alwin G. Schuller, Jim Eyles,Duncan Jodrell

Journal for immunotherapy of cancer（2023）

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关键词
Adenosine,Macrophages,Tumor Microenvironment,Immunity,Innate,Immunotherapy
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