The relationship between urinary bisphenol A levels and body weight in children Bisphenol A levels and body weight

ANNALS OF CLINICAL AND ANALYTICAL MEDICINE(2021)

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Abstract
Aim: Bisphenol A (BPA), one of the most commonly produced and used endocrine disruptors in the world, is a chemical employed in the production of polycarbonate and epoxy resins. A significant relationship between urinary BPA levels and obesity has been shown in clinical trials. This study aimed to investigate the relationship between urinary BPA levels and obesity in childhood. Material and Methods: The study was performed with a total of 172 children: 75 participants with a weight status of obesity. 33 participants with a weight status of overweight, and 64 participants with a weight status of normal. Sociodemographic data, family history of chronic diseases, preferred water/beverage/food containers, prepared water/beverage/food consumption, screen-based behavior time, and regular physical activity rates of children data were gathered from parents via questionnaire. Results: Among 172 children, 47.7% (n = 82) were males and 52.3% (n = 90) were females. The mean age was 11.7 +/- 3.3 (4-18) years. The age and gender distribution was similar between the body mass index groups. The total screen-based sedentary behavior time was higher in the obese group than in the normal weight group: 85.6% (n = 143) of all participants drank water from plastic bottles. Socio-demographic and anthropometric features, total time of screen-based sedentary behaviors, usage of plastic water/beverage/food containers, pre-packaged water/beverage/food consumption, and IR detection rates were similar between the BPAmcg/kreat percentile groups. Discussion: BPA was detectable in all urine specimens. As the urinary BPA level increased, BMI SDS increased. Urinary BPA levels were not associated with IR.
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Key words
Bisphenol A, Childhood, Insulin Resistance, Obesity
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